About

Sachel Mok is an Assistant Professor in Medical Sciences, Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center. Sachel has more than 16 years of research experience in malaria.

Her primary research interests are centered on understanding the mechanisms of antimalarial drug resistance, and elucidating the genetic determinants of fitness and transmission in Plasmodium falciparum parasites using a combination of systems-wide functional genomics and molecular genetics approaches.

Sachel graduated with a PhD in 2013 under Dr. Zbynek Bozdech, at Nanyang Technological University, Singapore, where she characterized the transcriptomes of artemisinin-resistant clinical isolates in the large-scale Tracking Resistance to Artemisinin Collaborative study (Mok et al, Science, 2015). Sachel was awarded the prestigious Human Frontiers Science Program (HFSP) Long term Fellowship in 2016 and subsequently moved to Columbia University Irving Medical Center in New York to work with Dr. David Fidock. Her current research focuses on the discovery of molecular determinants of resistance to antimalarial drugs, and genetic markers that underlie parasite’s fitness and transmission through the use of P. falciparum genetic crosses conducted in humanized mice. She is also highly interested in creating high throughput in vitro assays to enable molecular surveillance of emerging drug resistance in the field.

Her favourite leisure activities include inline hockey, scuba-diving and searching for new gastronomical experiences.

 MEDIA

2016 Human Frontier Science Program Long-Term Postdoctoral Fellowship Interview

PUBLICATIONS